Vitamin D in the time of the coronavirus (COVID-19) pandemic - a clinical review from a public health and public mental health perspective
Ther Adv Psychopharmacol 2021 Jul 9; doi: 10.1177/20451253211027699.
Ursula Werneke 1, Fiona Gaughran 2, David M Taylor 3
Study is a wide ranging overview of COVID and Vitamin D,
has a nice chart of the immune system
and a table of Vitamin D levels around the world
Immunity category in VitaminDWiki starts with
see also
Virus category listing hasOverview Influenza and vitamin D
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18 titles in VitaminDWiki contained INNATE or ADAPTIVE as of Jan 2023
Increasing publications on vitamin D and Infection
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 Download the PDF from VitaminDWiki
Individuals with serious mental disorders (SMD) may have a higher risk of vitamin D (VIT-D) deficiency. They also experience higher mortality because of coronavirus disease 2019 (COVID-19) infection. Therefore, we have conducted a comprehensive review to examine the significance of VIT-D for public health and public mental health during the ongoing COVID-19 pandemic. This review had three specific aims, from a global perspective to (a) create a profile of VIT-D and review the epidemiology of VIT-D deficiency, (b) explore VIT-D deficiency as risk factor for SMD and COVID-19 infections and (c) examine the effectiveness of VIT-D supplementation for both conditions. We found that, in terms of SMD, the evidence from laboratory and observational studies points towards some association between VIT-D deficiency and depression or schizophrenia. Mendelian randomisation studies, however, suggest no, or reverse, causality. The evidence from intervention studies is conflicting. Concerning COVID-19 infection, on proof of principle, VIT-D could provide a plausible defence against the infection itself and against an adverse clinical course. But data from observational studies and the first preliminary intervention studies remain conflicting, with stronger evidence that VIT-D may mitigate the clinical course of COVID-19 infection rather than the risk of infection in the first place. From a public health and public mental health point of view, based on the currently limited knowledge, for individuals with SMD, the benefits of VIT-D optimisation through supplementation seem to outweigh the risks. VIT-D supplementation, however, should not substitute for vaccination or medical care for COVID-19 infection.
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Vitamin D helps both the Innate and Adaptive immune systems – July 2021
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50 visitors, last modified 18 Dec, 2024, |
ID | Name | Uploaded | Size | Downloads | |
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15955 | Inate adaptive.jpg | admin 22 Jul, 2021 | 215.11 Kb | 399 | |
15954 | Mental Health COVID-19 and vitamin D.pdf | admin 22 Jul, 2021 | 790.32 Kb | 438 |